What are the possible negative Anadrol side effects for male bodybuilders?
Anadrol is renowned as the extreme and potent of the anabolic steroids, with specific concerns in relation to hepatotoxicity.
The high levels of hepatotoxicity linked allow for Anadrol usage that does not exceed four to six week periods.
Another severe side effect of Anadrol is its high Estrogenic activity even though it lacks the capability of conversion to Estrogen by using the aromatase enzyme.
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This Anadrol characteristic, along with its other side effects, is an enigma.
For the purpose of illustration, it is common knowledge that Anadrol maintains a lower androgenic rating of forty-five in contrast to the Testosterone, Anadrol ranking of one hundred.
Nevertheless, there are individuals, who experience substantial androgenic side effects.
This sole reason proves that Anadrol is not a suitable anabolic steroid for beginners.
Although, it is appropriate for the intermediate to advanced levels of anabolic steroid users.
The drug Anadrol presents as a severe Estrogenic compound.
However, its Estrogenic action is not derived from the transformation of Anadrol into Estrogen, because it lacks the chemical ability to change into Estrogen by way of its interaction with the aromatase enzyme.
The cause of these Estrogenic side effects is unknown, but there is speculation that Anadrol performs as an Estrogen in diverse tissues of the body.
The Estrogenic side effects that produce apprehension involve the retention of water and fat, bloating, weight gain, as well as the development of gynecomastia, which is the benign enlargement of breast tissue in males.
Since Anadrol does not aromatize into Estrogen, aromatase inhibitors are of no use in fighting the Estrogenic side effects of Anadrol, such as bloating or water retention.
This failure to resist water retention and bloating, using aromatase inhibitors, offers no protection in regards to the side effect of bloating and extra water weight.
Dietary adjustments will supply some defense, although there are limitations with these results.
A Selective Estrogen Receptor Modulator or SERM such as Nolvadex, will prohibit the development of gynecomastia.
Be mindful, that SERMs obstruct the action of Estrogen only at receptor sites for breast tissue. There is no reduction of complete Estrogen levels in the body.
Therefore, this treatment offers no resolution for water retention and bloating issues.
Some theorize that the Estrogenic action of Anadrol 50 results from progestogenic activity connected with this drug, but this Estrogenic activity is equivalent to the protestogenic action linked with Nandrolone.
However, there is no evidence to sustain this theory. One Anadrol study, that examined probable progestational activity, resolved that it displays no progestogenic qualities or actions.
The androgenic rating of Anadrol is half as low as Testosterone.
Anadrol maintains an androgenic rating of forty-five as compared to Testosterone, which has a rating of one hundred.
Conversely, user log experiences report that Anadrol side effects have a strong androgenic element that does not correspond to its lower rating.
Anadrol has been verified to transform into Dihydrotestosterone despite its attribute as a DHT derivative.
There is no conversion of Anadrol into DHT through the five-alpha Reductase enzyme, because its quality as a DHT derivative prohibits interaction with this enzyme.
Studies reveal that simple metabolism of Anadrol in the body eliminates the two-hydroxymethylene group from Anadrol.
A variation of its parent hormone DHT diminishes Anadrol into a more potent androgen known as seventeen-alpha-methyl dihydrotestosterone, which is also known as Mestanolone.
The androgenic rating of Mestanolone ranges from seventy-eight to two hundred fifty-four, and the outermost range is three times more powerful than the androgenic strength of Testosterone.
As a result, many individuals experience more intense androgenic Anadrol side effects than those reported from the sole use of Anadrol.
Androgenic side effects entail increased sebum secretion that produces oily skin and acne, increased hair growth on the face and body, and a greater possibility of Male Pattern Baldness or MPB in individuals with a predisposition to this genetic trait.
The probable side effect that encompasses the suppression or possible cessation of endogenous natural Testosterone is generated by all anabolic steroids including Anadrol.
In reality, the crash experienced after a cycle of the compound Anadrol is the most awful of all the anabolic steroids.
For most users, Anadrol allows for exorbitant increases in muscle mass in an exceptionally short span of time.
The resulting expectation, in contrast, is that this mass will dissolve in an equivalent short time.
The weeks that follow a cycle of Anadrol, produces intense weight reduction due to the loss of water retention generated by the compound.
It is possible to retain muscle mass through the rapid reestablishment of endogenous Testosterone production with the integration of an exceptionally potent Post Cycle Therapy or PCT program.
This is incorporated subsequent to the conclusion of a cycle, which makes use of compounds that stimulate Testosterone.
A major Anadrol side effect relates to hepatotoxicity, which is liver damage induced by chemicals.
Anadrol is C17 Alpha Alkylated, which is a principal factor responsible for the hepatotoxic effects of the compound.
To the contrary, an intriguing fact is that Anadrol has a structural element known as a saturated A ring, which is thought to diminish the hepatotoxicity of the compound.
Regardless of this fact, indications confirm that Anadrol still produces an inordinate amount of hepatotoxicity in the body.
Research studies have been conducted in which fifty to one hundred milligrams of Anadrol is administered on a daily basis to thirty-one male HIV positive test subjects over a time period of twelve weeks.
In seventeen percent of the subjects, the results revealed substantial increases in y-glutamyltransferase or GGT.
In addition to these findings, there were inordinate bilirubin increases in ten percent of the subjects, and serum albumin demonstrated increased levels in twenty percent of the subjects.
Numerous individuals have a diagnosis of lethal liver tumors known as peliosis hepatitis, which have been associated with the use of Anadrol.
The recommendation is to use Anadrol sensibly for periods that extend no longer than four to six weeks.
There is a critical recommendation that users supplement with a verified liver support and health supplement, such as TUDCA/UDCA along with the usage of oral anabolic steroids.
The most prominent and severe Anadrol side effect is cardiovascular strain or damage.
Cardiovascular strain and negative cholesterol fluctuations are standard side effects for all anabolic steroids, and oral steroids in particular.
This extreme side effect entails the decrease of the good cholesterol or HDL along with increases of the bad cholesterol or LDL, which causes severe strain on the heart. The fluctuations in cholesterol result in a greater risk of arteriosclerosis.
Dosage determines the degree of negative effects and risks related to these cholesterol level variations.
Higher doses intensify the negative aspects or side effect of cardiovascular risks.
The period of use, and method of administration are factors that also affect these negative cholesterol deviations.
As it relates to the course of administration, oral anabolic steroids are noted to have a significantly extreme negative impact on cholesterol as compared to injectable anabolic steroids.
This is the case, because liver function serves as the cholesterol-processing center for the human body.
In addition to this, the increased hepatotoxicity linked to anabolic steroids will produce more extreme negative cholesterol fluctuations.
Anadrol has an especially negative reputation for this, as it has an exceptionally high resistance to structural breakdown in the liver.
Medical studies were conducted on a group of males, which were administered fifty to one hundred milligrams of Anadrol during a twelve-week period.
The results revealed extremely dangerous and significant increases in LDL or bad cholesterol, and a substantial nineteen to twenty-three point reduction of HDL or good cholesterol.
Users of oral or injectable anabolic steroids need to take applicable precautions that entail suitable modifications in their dietary routines, which will stimulate beneficial base line cholesterol levels and fluctuations.
This particularly applies with the administration of anabolic steroids using the cycling method, and includes the use any form of cardiovascular health support supplements.
Anadrol side effects need to be controlled if you want to get the best results from your steroid cycle.