Anadrol is an Anabolic/Androgenic Steroid. It is also known as Anadrol 50 and popularly called A50 by athletes.
It was initially developed for the treatment of some medical condition such as osteoporosis and anemia.
The active ingredient for this androgen is Oxymetholone and it is considered the most powerful androgen available.
This compound was produced in 1960 by Syntex, an international pharmaceutical company.
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Anadrol is used in the treatment of anemia because of its ability to stimulate the production of red blood cells.
It achieves this by stimulating the production and secretion of erythropoietin, which is responsible for the production of red blood cells.
It is also used to stimulate muscle growth in underdeveloped or malnourished patients. It increases appetites as well as aids in gaining strength.
Oxymetholone is approved by the Food and Drug Administration (FDA) for medical purposes only.
Many athletes, body builders and weight lifters use this drug to enhance the muscle mass and performance even though, it is prohibited by many sporting authorities.
Anadrol have become even more popular with the discovery of the huge benefits of Anadrol in the treatment and management of HIV wasting syndrome.
Anadrol is being produced and sold in many countries.
It is used in the bulking or cutting cycle and it is the most powerful steroid in the market that produces the desired result within the shortest possible time.
Though, this steroid produces water retention and increases the elasticity of the muscle.
The ability of this steroid to cause water retention is due its estrogenic activities. This presents the risk of gynecomastia among men.
This steroid usually inhibits the body’s natural production of hormones especially, Testosterone.
It changes the blood lipid profile leading to the increase in LDL (bad cholesterol) and decrease in (HDL) good cholesterol.
This has some negative health implications on the users of this steroid.
As a result of the modification in the structure of this steroid it can be administrated orally.
This produces some level of toxicity to the liver and appears to be the major concern of almost all massive users of Anadrol.
But, this can be prevent or reduced to an acceptable level if the follow the recommended dosage.
Anadrol comes in different forms. The commonest forms are the 50mg tablets, capsules and injections. Recently 75mg tablet are seen in the market.
Oxymetholone is derived from dihydrotestosterone (DHT) and will inhibit the body’s natural production of hormones such as testosterone.
The chemical name for Oxymetholone is 17?-hydroxy-2-(hydroxymethylene)-17-methyl-5?-androstan-3-one.
The inactive ingredients in Anadrol are Povidone, Starch, Magnesium stearate and lactose.
Anadrol is not only derived from dihydrotestosterone but also have been modified at the 17th carbon position just like some anabolic steroid such as Winstrol and Dianabol.
Anadrol possesses C17 alpha alkylation. This enables it to survive the oral route of administration.
C17 alpha alkylation allows Oxymetholone to survive the first pass through the liver and ensures that it is not degraded by the liver.
This mechanism provides availability of the steroid for activity in the system even though, it produces some level toxicity to the liver.
Oxymetholone differs from dihydrotestosterone by the presence of 2- hydroxymethylene group.
It is reduced to Anadrol potent androgen 17 alpha-methyldihydrotestosterone by the removal of the 2- hydroxymethylene group.
Anadrol is required in more quantity per dosage than other steroids.
This is due to the fact that other steroids such as Dianabol or Winstrol have a higher affinity for the androgen receptors than Anadrol.
Therefore, they are effective even in smaller doses. This is quite different with Anadrol.
This feature makes Anadrol available in higher concentration per tablet (usually 50mg per tablet) compared to other Anabolic steroids.
In addition, this characteristic also produces increase level of toxicity to the liver than other steroids.
In order to monitor and check the effects of Anadrol, users are advised to stay within recommended dosage.
It is important that users limits the intake of this steroid to 6 weeks and have their liver activity monitored by their Doctor.
Furthermore, the low binding capability of Oxymetholone makes it a very powerful component in any bulking circle.
This is because there are a lot of unbound androgen receptors. Therefore, it won’t be competing for other receptor sites with other steroids in the stack.
In addition, Anadrol has the ability to lower the serum’s level of Sex hormone Binding globulin (SHBG).
Consequently, this increases the amount of free unbound steroids that are available in the system for muscle development.
Despite that Oxymetholone comes with some unfavorable effects. It is still the most powerful androgenic steroid available.
The benefits of this compound cannot be overemphasized in the treatment of Anemia and HIV wasting syndrome.
In a study conducted on HIV patients who were placed on Anadrol therapy, the patients gained considerable amount of pounds while their counterparts who were not on the drug were losing weight.
This study indicated that the weight gain peaked at about 20 weeks of the 30 week test.
It was obvious that there was no significant gain in weight after the 20 weeks. This implies that the last 10 weeks didn’t produce significant weight gain.
This study reveals how important Anadrol is in the treatment of muscle wasting.
However body builders, weight lifters, athletes and others are not advised to stay on this therapy for such a length of time due to the toxicity.
Those who took part in the study were monitored for toxic effects of the drug within those weeks of the study.
Anadrol is used by many body builders to develop hard and big muscles. It also helps in the development of lean muscle mass.
In addition, Anadrol enhances the overall outcome of training, as it increases the size and strength of the muscle.
Due to the increase in the production red blood cells which aids in the circulation of oxygen, Anadrol brings about quick recovery during strenuous activities and eliminates or reduces the incidences of muscle cramps.
This is achieved as the abundance of oxygen circulated aids in quick recovery and prevents accumulation of lactic acids that often leads to muscle cramps.
One major role of Anadrol is that it promotes Nitrogen retention and prevents muscle breakdown leading to muscle growth.
This steroid encourages the storage of enzymes such as Adenosine Triphosphate (ATP) to produce Adenosine Diphosphate (ADP).
This plays an important role in muscle movement, growth and also increases muscle strength.
Anadrol have also been used by many because of its ability to increase joint lubrication and lean muscle.
These characteristic helps to prevent the injuries among athletes, body builders and people who do strenuous activities.
Body builders love using Anadrol because:
1. It promotes Nitrogen retention. This is an indication of development of the muscle from protein.
2. It prevents catabolism. Therefore, lean muscle is not broken down.
3. It can boost protein production in combination with high calorie diet.
4. Increases oxygenation of the blood.
The growth of muscle is accelerated as the muscle is stimulated periodically with exercise, workouts and trainings.
This is the principle of muscle growth employed by weight lifters. Anadrol plays an important role in the bulking cycle.
Many users who have used Anadrol in two small cycles of 8 weeks with a 2 months gap have obtained great results. Anadrol effects works well with many bulking stacks – especially with Dianabol.
Rapid development can be obtained when stacked with injectable and with the addition of testosterone. However, it have been identified that adequate sleep helps in bringing about the desired results.
At least 8 hours sleep each night is recommended. Inadequate sleep can affect the progress of users of Anadrol.