Oxymetholone is an oral anabolic steroid with the brand names of Anadrol and Anadrol-50, and it is reputed to have maximum potency compared to any conventional oral anabolic steroid in existence today.
However, there is significant deliberation about the potency ranking of Oxymetholone as a conventional oral anabolic steroid as it is considered equal to Dianabol.
Anabolic steroids such as Dianabol are deemed conventional, because they have been developed and marketed for use by bodybuilders and athletes for years.
These conventional anabolic steroids exclude designer anabolic steroids, recently created and unknown compounds, in addition to anabolic steroids that remained in the Research and Development phase of creation. Click here to buy legal Anadrole online, without a prescription.
Anabolic steroids significantly more potent than Oxymetholone exist, but they are designer anabolic steroids or synthetic compounds.
To the contrary, they are rarely found or used, because they are too dangerous. In 1959, Oxymetholone facts were first published in this country.
Subsequently, the publishing of similar data for Anadrol led to it being marketed in the United States by Syntex as Anadrol-50, and Parke Davis & Co. manufactured it for sale under the brand name Androyd during the period of the early 1960s.
There are established medical and therapeutic usages for debilitating geriatric illnesses, diseases that cause muscular atrophy, weight gain, and the preservation of muscle mass during disease or disability.
Other uses involve treatment for osteoporosis, fighting infection, gastrointestinal diseases, and a number of other catabolic conditions related to cell breakdown.
Anadrol 50 was widely used for the treatment of anemia, since it accelerated red blood cell and hemoglobin production, and it stimulates erythropoiesis more than other anabolic steroids.
Oxymetholone stimulates red blood cell production fivefold.
Initial supplies of the drug comprised two point five milligram, five milligram, and ten-milligram tablets with a dosage recommendation of around two point five milligrams administered three times per day.
As with many anabolic steroids, with the passage of time, the FDA or Food and Drug Administration restricted its medical uses to the exclusive treatment of anemia in order to stimulate a more intense red blood cell production effect.
This fostered an increased strength to fifty-milligram tablets, which prompted the brand name Anadrol-50.
Advance treatments and techniques to help anemic patients, terminated Oxymetholone use in the United States market.
Part of the reason for this was the mass hysteria against steroid use that occurred in the early 1990s, which contributed to its disappearance from markets in the United States and global marketplaces as well.
In spite of all these situations, Syntex sold the rights for the compound in the 1990s. Unimed Pharmaceuticals reestablished Anadrol in North American markets during 1998, with its medical uses extending to the treatment of HIV/AIDS patients.
Oxymetholone is a derivative of Dihydrotestosterone or DHT, belonging to the classification of anabolic steroids.
In addition, they are all derivatives of DHT the original anabolic steroid. The collective factor in all of these DHT derivative equivalents is that they are all altered forms of DHT.
This fact translates with DHT thought of as the antecedent or progenitor hormone of these anabolic steroids.
Oxymetholone diverges from its source hormone DHT by means of the inclusion of an attached methyl group, as well as a 2-hydroxymethylene group attached to a carbon in the first cycloalkane ring chemical structure of the steroid.
Alterations such as these allow for continued activity in muscle tissue, since Dihydrotestosterone would typically lack activity through its reduction to other metabolites once entering the muscle tissue.
The 3-hydroxysteroid dehydrogenase enzyme is accountable for this occurrence related to Dihydrotestosterone, which exists in substantial amounts within muscle tissue.
With the chemical modifications mentioned, this enzyme does not interact with Anadrol.
This compound, as a result, is excessively active in muscle tissue that has the effect of its exorbitant potency.
Oxymetholone retains an anabolic rating of three hundred twenty, which is in excess of three times the potency of Testosterone that has an anabolic rating of one hundred.
It has also been determined that Anadrol also has diminished androgenic potency levels in contrast to Testosterone, though Oxymetholone holds an androgenic rating of forty-five compared to an androgenic rating of one hundred for Testosterone.
An intriguing property of Anadrol, in addition to it being a derivative of DHT, involves its exorbitant levels of Estrogenic activity.
The DHT-derivative anabolic steroids have the property of conversion into Estrogen via the aromatase enzyme, and consequently prompt no Estrogenic effects.
Anadrol is renowned for creating gynecomastia, water retention, bloating, and different other Estrogenic effects on the body even without transforming into Estrogen.
Some consider that the estrogen affects specific tissues, as opposed to all tissues.
Be mindful that even though Anadrol is a DHT-derivative, it does not provide the experience of obtaining the lean and hard gains that are normal for DHT derivatives.
Anadrol has noted Estrogenic effects that are resistant to aromatase inhibitors since it is unable to transform into Estrogen.
Anadrol is an anabolic steroid that is activated orally, which translates as it having been C17 Alpha Alkylated to enable the anabolic steroid initial access to the liver without being destroyed through metabolism by the liver.
However, it has a reputation of extreme hepatotoxicity, which is chemically induced liver damage.
Anadrol has chemical deviations and chemical structure such as C17 Alpha Alkylation that makes it inordinately resistant to hepatic breakdown in liver metabolism.
The more excessive the resistance a substance has to hepatic breakdown, the more experiences will relate to severe toxicity as well as stress and pressure on the liver.
Anadrol is distinguished as the maximum liver toxic oral anabolic steroid conventionally available in the marketplace today.
Dosage of this steroid depends on the individual, the purpose and the cycle that the individual is running.
The use of most steroid produces a dose respondent curve which projects the level of progress to be made at each dosage and for a specified period of time.
However, it is interesting to note that the dose respondent curve for Oxymetholone levels out very quickly unlike many other steroids.
Individuals who take 50mg of Oxymetholone obtain good result, increasing the dosage to 100mg produces better results.
However, studies have shown that increasing the dosage above 100mg per day does not produce any significant improvement in the result obtained when compared to gains at 100mg.
Moreover, dosage above 100mg per day produces more side effects and is more toxic and injurious to the system.
Therefore, exceeding 100mg is not necessary as it increases cost and toxicity with no significant improvement.
A study done revealed that when the dose of Anadrol was doubled from 50mg to 100mg, the user almost doubled the strength gained when compared against subjects that just took the normal dose of just 50mg.
However, the subject whose dose were doubled experienced more gain in lean body mass and the lost more fat when compared to those took 50 mg of Oxymetholone.
However, the fat loss and lean body mass gain wasn’t as impressive as the differences in the strength gained between the sets of subjects.
In order to obtain the desired result while using Anadrol, it is important that you follow a pre-defined cycle.
Oxymetholone steroids can be used in the bulking and cutting cycle with the former widely employed. The Majority of cycles are usually for the bulking cycle.
Nevertheless, some people add Oxymetholone tablets into their cutting phase. This is often seen among competitive body builders.