What is Anadrol and what are the effects and benefits of this anabolic steroid?
Many users of anabolic steroids consider Anadrol as the most potent steroid available.
Anadrol is a brand name for Oxymetholone and is a very powerful androgen. This compound was produced in 1960 by Syntex, an international pharmaceutical company.
It was developed for the treatment of some medical conditions such as anemia and osteoporosis. It does this by stimulating the production of red blood cells.
It stimulates the production and secretion of erythropoietin. It increases appetites as well as aids in gaining strength.
Many athletes, body builders and weight lifters use this drug to enhance their muscle mass and performance. Click here to buy legal Anadrole online, without a prescription.
In the early 90s, better alternative to treating the earlier mentioned medical conditions were discovered and produced.
This led to the stoppage of the production of Anadrol by Syntex in 1993 in the United States.
Many other companies in other countries also halted the production of Oxymetholone at that time.
This created some concern among non-medical users of Anadrol who thought that this would be the end of this steroid.
However, with the discovery of the huge benefits of Anadrol i50 n the treatment and management of HIV wasting syndrome, It has since being produced and sold in many countries including the United States again.
Presently there are different brand names of Anadrol in different countries licensed by Syntex to produce it for medical purposes.
Today it is still being used by many body builders and other sport persons.
Experience have shown that individuals experimenting with this steroid can gain over 20 pounds of massive bulk in less than 6 weeks. This can be achieved with just 50-100mg of Anadrol per day.
This is quite impressive. Little wonder, many of its users cannot do without this steroid.
Anadrol produces fuller and smoother muscles. Though, this steroid produces water retention which many body builders detest so much.
Nevertheless, it increases the elasticity of the muscle and drastically reduces the chances of injuries that results due to heavy lifting.
Pectoral and bicep tissues are easily torn while heavy lifting. This is common among users of steroids.
Despite, the great results obtained from using Anadrol it poses the risk of the development of gynecomastia among men.
This is due to the effects of estrogen. Estrogenic effects are reduced drastically by the use of Clomid or Nolvadex.
Anadrol does not aromatize. Therefore, the use of strong anti-aromatase compound such as Resveratrol, Femara, Aromasin and Arimidex are not required.
This steroid usually inhibits the body’s natural production of hormones especially, Testosterone. This appears to be the major concern of almost all massive users of Anadrol.
But, this can be prevent or reduced to an acceptable level.
Oxymetholone is derived from dihydrotestosterone (DHT) and will inhibit the body’s natural production of hormones such as testosterone.
It does not directly convert to estrogen in the body but, this drug comes with estrogenic effects. Many believe that the estrogenic effect are as result of progestational activities which is not strictly estrogenic.
However, progestin and estrogen have similar effects. Nevertheless, medical report shows that there is no significant progestational effect in steroids such as Oxymetholone or Methandrolstenolone.
These findings suggests that the estrogen receptors may be intrinsically activated by Oxymetholone but are not converted to estrogen.
This steroid produces many androgenic effects such as oily skin, facial hair growth and male pattern hair loss in women and acne.
In some women irreversible virilization may occur. The severity of androgenic effects may be severe in some women while, it is mild in others.
Thus, women should be cautious as the use this steroid and it might be a wise decision for some women to stay away from this steroid due to their sensitivity to the drug.
It is advised that women who use this steroid seek the advice of their Doctor and they should use the drug at a fairly low dosage.
Anadrol is known for its water retention. To some, this is a disadvantage while, to many this is of little importance.
However, few people prefer some level of water retention as it enables the muscle contract better and provides some lubrication to the joint.
This is so because some retained water accumulates around the connective tissue. Water retention also allows the muscle to be more elastic.
This is important as it reduces the chance of injury especially among weight lifters.
Of utmost important to the body builders and weight lifters, water retention does not give the muscle that attractive hard, veiny and smooth look that they strive to obtain.
Though, users report that they feel bigger and stronger.
Anadrol is not only derived from dihydrotestosterone but also have been modified at the 17th carbon position just like some anabolic steroid such as Winstrol and Dianabol.
Anadrol possesses C17 alpha alkylation. This enables it to survive the oral route of administration.
C17 alpha alkylation allows Oxymetholone to survive the first pass through the liver and ensures that it is not degraded by the liver.
This mechanism provide availability of the steroid for activity in the system even though, it produces some toxicity to the liver.
Oxymetholone differs from dihydrotestosterone by the presence of 2- hydroxymethylene group.
It is reduced to Anadrol potent androgen 17 alpha-methyldihydrotestosterone by the removal of the 2- hydroxymethylene group.
Despite the similar C17 alpha alkylation present in some other common steroids such as Dianabol or Winstrol, Anadrol requires more quantity of the steroid per dosage than other steroids.
This is due to the fact that these other steroids have a higher affinity for the androgen receptors than Anadrol.
Therefore, they are effective even at smaller doses. This is quite different This lowered affinity for androgen receptor explains why Anadrol is available in a fairly larger tablet concentration of 50mg tablets rather, than smaller concentration per tablet as seen in other similar steroids.
This characteristic of Anadrol 50 produces more toxicity to the liver since, more amount of the steroid needs to be taken in order to compensate for its low affinity to the androgen receptors.
It is not surprising that some people have suggested that the high dosage of Anadrol may be responsible for the linkage of the use of steroids to liver cancer.
In order to eliminate or reduce the effects of Anadrol, users are advised to stay within the recommended dosage.
It is important that users limit the intake of this steroid to 6 weeks and have their liver activity monitored by their Doctor.
The dosage is much higher than other androgenic steroid. This is due to the fact that it has lower affinity for androgen receptors.
For medical purposes Anadrol is taken at a dose of 1-5mg/kg. This is quite high when the actual amount is calculated for an adult. Athlete and sportspersons do not need this high dosage.
Because of the potency of Anadrol 50 pills, it is recommended that users seek medical advice before embarking on the use of this steroid.
Your Doctor should monitor your system as you take the drug and this should be the basis for deciding the maximum amount of Anadrol to be taken.
In addition, this compound should not be used for more than 6 weeks. This is to prevent the occurrence of problems associated with liver toxicity.
Dosage depends on the individual, the purpose and the cycle that the individual is running.
Sudden discontinuation of Anadrol usually leads to some unfavorable side effects.
As part of the effects associated with sudden stoppage of the use of Anadrol, is the sudden drop in water retention that normally leads to sudden drop in weight.
The most important concern of sudden discontinuation of the use of Anadrol is the restoration the body’s natural production of testosterone that have been inhibited during the Anadrol cycle.
To aid the body return back to its natural production of steroids, using of Clomid/Nolvadex and HCG have been recommended and it works well on many users.
Some people believe that gradually reducing the dose of Anadrol during stoppage solves the issue of restoration to the natural production of testosterone.
This is inefficient as it does not raise the level of testosterone immediately. Without using the necessary drugs, muscle gained during the cycle may be lost.
Many have maintained their previously gained muscle mass as they discontinued Anadrol with the use of HCG and Clomid/Nolvadex.
Another effective method of retaining new muscle is to switch over to Deca-durabolin before stoppage. This steroid hardens the new muscle mass.
As individuals discontinues without pronounce crash, drop in water retention produces better muscle mass.
As have been stated earlier, Anadrol is a powerful androgen that comes with some effects.
Some people have attempted to reduce the androgenic nature of the testosterone to some level. They do this by using the reductase inhibitor Finasteride (Proscar).
This attempt is futile as this enzyme does not play a role in the mechanism of action of Anadrol.
Some of the androgenic effect of Anadrol includes; acne, body and facial hair growth, deepening of the voice and oily skin.
Oily skin may become severe in some, that it may require treatment with Accutaine. This drug reduces the secretion of oil by acting on the sebaceous gland.
Other effects of this oxymetholone steroid includes male pattern hair loss (or baldness), nausea, high blood pressure, gynecomastia, mood and mental problem, changes in libido, irregular menstruation, enlargement of the clitoris, frequent and persistent erection and increase in the cholesterol level of the individual.
Liver toxicity and its effect are also concerns associated with the use of almost all steroid.
These symptoms often manifests when individuals use large doses of Anadrol 50 or when they use it for a prolonged period of time. Side effect are usually mild to moderate among users who stay within the recommended dosage.